The NRI Director's Office oversees the Institute's business-winning, marketing, financial planning and policy-direction. It includes:
| Poulter, Dr Guy | Director |
| Birkbeck, Karen | Systems Development Manager |
| Collins, Joyce | Laboratory Manager |
| Downard, Joanne | Business Development Administrator |
| Field, Sharron | Finance Administrator |
| Holdsworth, Ron | Programmer |
| Jolliffe, Flavia | Statistician |
| Keane, Evie | Laboratory Manager & Administrative Support |
| Linton, John | Commercial Director |
| McAvoy-Marshall, Heather | Quality Assurance and Health & Safety Co-ordinator |
| Morley, Natalie | Laboratory Technician |
| Oliver, Katy | Administrative Assistant |
| Raven, Samantha | Contract Co-ordinator |
| Westby, Prof. Andrew | Director of Research and Enterprise |
| Guyatt, Amy | Management Accountant Attached to Finance Department |